https://www.nathansonlab.com/welcome daily 1.0 2026-02-03 https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1550189791137-D06W5KDVUCT82L0HG2JO/Banner_image%25252Bcrop.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1664391432601-GGXG067E3RU0YAEHT7EK/Donate.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549491512765-S92TCTMU0O5VKA95WFMG/Biology_small.png Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1550189466861-07A5XXD7PII91EL63C4F/Drugdev_small.png Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549478008865-ORY10IUACGEM6QNVSH5E/GliomaPDOX_small.png Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549473248815-V7BUAQFKC7CN53R0E2T7/molecular_small.png Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/6d4ac31d-e689-4ad9-8fa0-70a5beba39ed/41467_2024_54138_Fig1_HTML.png Welcome - Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma Genomic profiling often fails to predict therapeutic outcomes in cancer. This failure is, in part, due to a myriad of genetic alterations and the plasticity of cancer signaling networks. Functional profiling, which ascertains signaling dynamics, is an alternative method to anticipate drug responses…. READ FULL ARTICLE https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/2e32d1d7-4b4d-4489-9eae-dfb7b169a890/CDKN2A+Cancer+Cell+Paper.png Welcome - CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis Malignant tumors exhibit heterogeneous metabolic reprogramming, hindering the identification of translatable vulnerabilities for metabolism-targeted therapy. How molecular alterations in tumors promote metabolic diversity and distinct targetable dependencies remains poorly defined… READ FULL ARTICLE https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1597780056269-TLWNMXW9DX74I3WHKBC8/ACS_figure_JT.jpg Welcome - Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors. The epidermal growth factor receptor (EGFR) is genetically altered in nearly 60% of glioblastoma tumors; however, tyrosine kinase inhibitors (TKIs) against EGFR have failed to show efficacy for patients with these lethal brain tumors… READ FULL ARTICLE https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549412041861-A46UCV2F9O5QK05IFSH6/p53publication.png Welcome - Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma. Cross-talk among oncogenic signaling and metabolic pathways may create opportunities for new therapeutic strategies in cancer…. READ FULL ARTICLE https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549412293279-DYOAH0ZYJ2FCJK6UPN1Z/Science.png Welcome - Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA Single-cell analyses of patient-derived models and clinical samples from glioblastoma patients treated with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) demonstrate that tumor cells reversibly up-regulate or suppress mutant EGFR expression… READ FULL ARTICLE https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1552431270305-2OEZ71W9HESINFPGD6YH/Summer+Lab+Party+2017.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1552431971009-2OJMHOLH7DJ8A5B4PPP0/DSC_0665.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1552431221904-WCXCL49XMO3QF2U2PNYD/NB+SNO+2018.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1552431287961-XHA7UB5YGRPXO71OHBPA/lab+pic+summer+2018.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1552431924861-IOT9AX0W2PS0VWTS776F/DSC_0655.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1555619214504-FNMD119544YR6R0EOER3/Group+Smile.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1601580170664-UB9S6XV2UJNCRLR2NVI5/SNO+2019.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1700617463659-L424F39WAWQELG7IQDL0/SNO2023.jpg Welcome https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1550438314403-YRAUK23D3SW4U8R5SJT7/IMG_1840Edit.jpg Welcome - Postdoctoral Researcher Open position in translational brain cancer research focusing on cell signaling and apoptosis. https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1560632628269-HVOCCUFIO54Y1HI1XWTW/IMG_3969-5.jpg Welcome - David Nathanson, Ph.D. Professor More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1573076423814-8202NUOYIZRU9VQE10QO/Elizabeth+Fernandez.jpg Welcome - Elizabeth Fernandez, Post-Doc Research Fellow Elizabeth Fernandez https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/221aaca5-148b-4674-a850-51839fc07354/DSC02212.JPG Welcome - Alex Sun, Post-Doc Research Fellow More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/427fb6e9-03df-4a6d-a74c-444df6625a4e/20240813_Jenna.jpg Welcome - Jenna Minami, Post-Doc Research Fellow More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1541381780577-MGAFUGZZ3TH55L0YDOIU/IMG_1980Edit.JPG Welcome - Nick Bayley, PhD Candidate Nick Bayley https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1f830c94-bc23-4b1a-aaa2-b04c57d1f5e2/20241121_Quincy.jpg Welcome - Quincy Okobi, PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1631127726704-6T1LVB9V1T9HHTWZ1ZT4/Marissa+Pioso.jpg Welcome - Marissa Pioso, PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1573075808106-FUI5INZIBULKC6CBTHRA/Jenny+Salinas Welcome - Jennifer Salinas, PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/6c56a715-e93c-416e-9eeb-c0eb57d4d90b/20240813_Dimitri.jpg Welcome - Dimitri Cadet, MD-PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/f638585f-a5ce-492a-b8cc-39f4327d6700/20240813_Armon.jpg Welcome - Armon Goshayeshi, PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/c2da47cd-788f-4d15-90dd-6a533da5dc56/20241112_Lisa-2.jpg Welcome - Lisa Cha, MD-PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/0a2a21ee-ffcb-4245-8d79-2c7b22c0c812/20240813_Tiff.jpg Welcome - Tiffany La, PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/cdce32a4-31a7-4ec8-b694-d3717c70d342/NathansonLab_Branding_Digital__Logomark_Color_Black%2BBlue.jpg Welcome - Jihui Sha, PhD Candidate More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1555524954080-PUK24MFJ3IH92R1NY9FR/IMG_1918Edit.jpg Welcome - Christopher Tse, Program Manager Chris Tse, SRA I Research Project >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/77ab3f49-aa2d-46b1-a879-4d86100f8aef/20241211_Michael.jpg Welcome - Michael Vigman, Drug Discovery More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/ec32e32d-ecb6-4599-8f59-57a8b158cd7c/20240813_Amir2.jpg Welcome - Amir Borujerdpur, Bioinformatics More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/d033b5ec-e66c-46c3-a067-f332bb720c97/20240813_Raul.jpg Welcome - Raul Davila, Model System Development More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/b28c06e0-3f95-4955-bf41-a47c54040e3b/20240813_Ron.jpg Welcome - Ronald Bernal, Model System Development More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/909315ec-594e-4f72-8b72-a5a642946867/20240813_Max.jpg Welcome - Max Johnson, in vivo Drug Development More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/a9918d31-a136-4ea9-84d7-40b34783ce9c/20240813_Ivan.jpg Welcome - Ivan Khoroz, in vivo Drug Development More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/0e3778d7-cbf9-4cb3-b073-379c2233fddf/20240813_Rashmika.jpg Welcome - Rashmika Kulshrestha, in vivo Drug Development More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/7353e333-2689-4ef0-b0bd-b0f4e05f0e65/MV_20250403_Edit_IMG_7508.jpg Welcome - Ethan Mach, Bioinformatics More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/ec2484c2-ce11-45dd-a4c3-70d62db13abf/20240813_Sarah.jpg Welcome - Sarah Lee, in vivo Drug Development More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/a2acd624-70ad-46db-86bf-60ff4d5e0a93/20240813_Toby.jpg Welcome - Toby Harris, Undergraduate Student Researcher Toby Harris More >> https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/339dc45e-c197-4959-9b30-aff357aabd81/20241113_Kailyn.jpg Welcome - Kailyn Kennada, Undergraduate Student Researcher https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/2233221b-08c7-49f9-9440-18964b9a072e/20241113_Caitlyn.jpg Welcome - Caitlyn Loo, Undergraduate Student Researcher https://www.nathansonlab.com/drug-discovery daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1547611493334-FHW8S25T0LAOITGNPCA1/IMG_1392Edit.JPG Drug Discovery https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1550189645921-P7KDH8PPHGKKEF6S0UW9/Drugdev+large.png Drug Discovery https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548194780995-AHVNR29XI6WOD13GZUMF/image-asset.jpeg Drug Discovery Dr. Jonathan Tsang https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628217998-8HO2N4RIXFHJU9U1DBFO/Quincy+Okobi.jpg Drug Discovery Quincy Okobi https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/a08da255-77bc-4089-9fef-a87fbb37f7cd/Timothy+Cloughesy.jpeg Drug Discovery Dr. Timothy Cloughesy https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/a27df6b9-162e-4509-914d-33d4937de7f2/Vjola+Haka.jpg Drug Discovery - Make it stand out Vjola Haka https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/275795fc-55ce-489e-b858-9a39adf4ee71/Rhea%2BPlawat.jpg Drug Discovery - Make it stand out Rhea Plawat https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548194896981-9YR6AYM120XWN8H6T9L4/peter.jpg Drug Discovery https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1604339698017-BBOXSMTJOMTPFGVZHXHL/Bobby%2BChong.jpg Drug Discovery Dr. Robert Chong https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1565042695350-CFXSUB61PPJSQRKW7X6Z/Lorenz.jpg Drug Discovery https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628182730-4Y41U88Y52JOJ1MFYJAO/dn.png Drug Discovery Dr. David A Nathanson https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548195032161-2JL4VIB3B86B3DKJU3T3/jung.jpg Drug Discovery https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/b254fb45-f472-4da2-bc57-9f6321b6d71d/20211015_DC_NathansonLab_Project_Graphic.png Drug Discovery - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1631126901247-QL3TE2CH2SH9X0LTHIL0/Dmitri+Cadet.jpg Drug Discovery - Make it stand out Dimitri Cadet https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/21ab8d96-2beb-4170-aca8-7d709b7b20e8/Medoly+Jiang.jpg Drug Discovery - Make it stand out Melody Jiang https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628294753-0RZT8KC399Z863CCI6ED/dn2.png Drug Discovery - Make it stand out Dr. David A Nathanson https://www.nathansonlab.com/post-doc daily 0.75 2019-02-17 https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1547607907682-GDHAE4FM6PRN541B7BEC/IMG_1840Edit.JPG POSTDOCTORAL RESEARCHER https://www.nathansonlab.com/gliomapdox daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1547611552166-81KA8Z9C5H8TPYOLFUN0/IMG_1510Edit.JPG GliomaPDOX https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549471927513-YMZ3S8X0HJAZ6LC3YURP/GliomaPDOX_image.png GliomaPDOX https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548195659982-8QR5KDU4YRLYCI51R3J2/chris.JPG GliomaPDOX Christopher Tse https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1573081860727-N4362IMSPE33AC7013M1/Jenny+Salinas GliomaPDOX Jennifer Salinas https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/b7c03d21-b7d5-4983-becc-59b7827aa2ca/Eunice+Lee.jpg GliomaPDOX - Make it stand out Eunice Lee https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628589486-14VJ7SK10RANB0SLDKTP/Andrew+Tum.png GliomaPDOX - Make it stand out Andrew Tum https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628356860-Q1DOGNHC0EWBJ4WP0B4D/dn.png GliomaPDOX Dr. David A Nathanson https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548196365774-36ED4TER4LQI1DNI6A2R/Linda.jpg GliomaPDOX Dr. Linda Liau https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1603303124206-GOMNVN6TI45DDJYUKJ9Y/Katelyn+Faircloth.jpg GliomaPDOX Katelyn Faircloth https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548196508630-AJZFQF3PLEPYL5ZDLOTI/rob.jpeg GliomaPDOX Dr. Robert Prins https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548196446341-4E9TXWQ5H420Q5S2LA0B/bill.jpeg GliomaPDOX Dr. William Yong https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548196135113-3R1T72YK87570K3XKPFN/Tim.jpeg GliomaPDOX Dr. Timothy Cloughesy https://www.nathansonlab.com/biology-of-cancer daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1547345929927-RJPX8D16VCYK4D1ZCGEH/DSC_0655.jpg Biology of Cancer https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1547612409622-GPYU3FVF6Z6571CD8WIO/Screen+Shot+2019-01-15+at+7.53.42+PM.png Biology of Cancer https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548193449675-SFCJNNET1YO0RUZ39EOP/IMG_1909Edit.JPG Biology of Cancer Elizabeth Fernandez https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628264756-5KWR340OY8NUSEDWOYZY/dn.png Biology of Cancer Dr. David A Nathanson https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548193512104-3RVPZ99RLBSYI5THRGN2/Tim.jpeg Biology of Cancer Dr. Timothy Cloughesy https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548193846171-0GS2KZQ6CS4QWT5XRVBK/Albert-Lai.jpg Biology of Cancer Dr. Albert Lai https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548183321328-TL5D6DS98P5YBUN95NDO/Screen+Shot+2019-01-22+at+10.52.10+AM.png Biology of Cancer https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548192918606-22YBX37QSD29BGXIK5WH/IMG_1989Edit.JPG Biology of Cancer Dr. Danielle Morrow https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548193897208-NN54EGD7Q87Q1RCNFZFV/steve.jpeg Biology of Cancer Dr. Steve Bensinger https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1603302555672-P53KI2MJ66LAL157CV1Q/Jenna+Minami.jpg Biology of Cancer Jenna Minami https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1549337052032-OU8UCNYL14TW25ZR6PZ0/image-asset.jpeg Biology of Cancer Dr. Hayato Muranaka https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1573081860727-N4362IMSPE33AC7013M1/Jenny+Salinas Biology of Cancer - Make it stand out Jennifer Salinas https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1548193050043-GD07C8TYM735MHXAZSC2/ajit.jpeg Biology of Cancer Dr. Ajit Divakaruni https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628861558-WX4AX9B0Z5MSXPSYV6JL/Rhea+Plawat.jpg Biology of Cancer - Make it stand out Rhea Plawat https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628294753-0RZT8KC399Z863CCI6ED/dn.png Biology of Cancer Dr. David A Nathanson https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/24ab15aa-620b-4493-a5d1-c711acd599c0/GBM+TME+Website.png Biology of Cancer - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1631125880847-LXWHKL1NQ1SQKKVJPTUA/Marissa%2BPioso.jpg Biology of Cancer - Make it stand out Marissa S Pioso https://images.squarespace-cdn.com/content/v1/5973e6f26f4ca31f2556fb92/1630628356860-Q1DOGNHC0EWBJ4WP0B4D/dn2.png Biology of Cancer - 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